Nanospears Unlocked: Targeted gene delivery with pin-point precision

Nanospears deliver genetic materials to cells with pinpoint precision

UCLA scientists developed a method to deliver biomolecules, such as genes directly into patient cells using microscopic nanospherical structures. These magnetically-guided nanostructures may enable safer, faster, and more cost effective gene therapies.

Paul Weiss is a distinguished professor of chemistry and biology, materials science and technology, and a member of UCLA’s Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research. He was the senior author of the research, which appeared in ACS Nano.

The process of replacing or adding missing genes to patient cells has shown great promise in treating a variety of diseases including hemophilia and muscular dystrophy. It is also a promising treatment for immune deficiencies, certain types of cancer, and other illnesses.


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