Unlocking the key to self-renewal: A protein’s role in human blood stem cell regeneration

Researchers have identified a protein that controls the self-renewal of human blood stem cells

UCLA scientists discovered that a protein is linked to the ability of blood stem cells in humans to self-renew. The team reported in a study that was published in Nature today, activating the proteins caused blood stem cells in lab conditions to self-renew by at least 12 fold.

The ability to multiply blood stem cells outside of the body can improve treatments for cancers such as leukemia, and many other blood diseases.

Dr. Hanna Mikkola has been studying blood stem cells since more than 20. She is a senior author of this study and a member of UCLA’s Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.


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