Reviewing Genomic Instability Cellular Senescence and Aging
We wanted to draw your attention today to a review that examines genomic instability, the accumulation of senescent cells, and their role in aging.
DNA damage is a major cause of aging
Many researchers believe that DNA damage or genomic instability is the primary cause of aging. The damage to and imperfect repair to the genomes stem and progenitor cell causes mutations that are then passed on to the somatic (or adult) cells created by these cells .