Unlocking NMN’s Secrets: The Reliable, Stable NAD+ Activator.

The Science Behind NAD+Activator NMN – A Stable and Reliable Molecule
Nad plus is effective for Alzheimer’s patients.

In June of 2,018 the World Health Organization (WHO) released the 11th edition of its International Classification of Diseases, and for the first time added aging.1 The classification of aging as a disease paves the way for new research into novel therapeutics to delay or reverse age-related illnesses such as cancer, cardiovascular and metabolic disease, and neurodegeneration.2,3 Nutrient sensing systems have been an intense focus of investigation, including mTOR (the mammalian target of rapamycin) for regulating protein synthesis and cell growth; AMPK (activated protein kinase) for sensing low energy states; and sirtuins, a family of seven proteins critical to DNA expression and aging, which can only function in conjunction with NAD+ (nicotinamide adenine dinucleotide), a coenzyme present in all living cells.4

The aging process is characterized by epigenetic changes, genomic instability and altered nutrient-sensing abilities, as well as mitochondrial dysfunction, stem cell exhaustion and dysregulated intercellular communications.7,8

NAD+ can be increased through activating enzymes to stimulate synthesis, inhibiting CD38, which degrades NAD+ and supplementing with NAD precursors such as nicotinamide riboside (NR) and nicotinamide monnucleotide(NMN).


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