Uncovering Mitochondrial Senescence in Cellular Senescence – A Novel Cancer Drug Delays Aging

Cancer Drugs Delay Cellular Senescence

Researchers discovered that mitochondria, the powerhouses in our cells, play a key role in the onset of senescence. This is a state where cells stop dividing and start to shut down.

Mitochondria cause cytoplasmic DNA and inflammation

New research shows that mitochondrial communication with the nucleus of each cell causes it to shut down, and then enter a senescent stage [1]. Dr. Peter Adams has been researching for over a decade how chromatin, a mixture DNA and proteins that are normally found in the nucleus of a cell, leaks out into the cytoplasm of senescent senescent. This leakage triggers a series of inflammatory signals that are associated with the onset of age-related diseases.


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