UCLA Study: Regulating scar tissue growth after heart attacks

How the body regulates the growth of scar tissue after heart attacks

It’s very interesting.

UCLA researchers have conducted a study on mice that could help explain why some people experience more scarring after a heartattack than others. The study published in Cell reveals that type 5 collagen, a protein, plays a crucial role in regulating scar tissue size in the heart.

Heart scar tissue is permanent and can reduce the ability of the heart to pump blood. It also increases the strain on the remaining heart muscles. Larger scars increase the risk of heart rhythm issues, heart failure, and sudden cardiac deaths in people.

\”Two people with the same severity of a heart attack may end up with different scar tissue,\” explained Dr. Arjun De, senior author of the study and a UCLA member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research. We set out to investigate why some hearts scarred more than others, given the correlation between scarring and survival rates. We can improve survival by reducing this scarring.


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