Simulations identify new way to reverse natural aging process in cells
A newly discovered enzyme can reverse the natural aging of cells.
A KAIST research team has provided insight into the complex mechanisms of cellular senescence. They also present a possible therapeutic strategy to reduce age-related illnesses associated with an accumulation of senescent cell.
Modeling molecular interactions has identified an enzyme which could be targeted in order to reverse the natural aging process known as cellular senescence. The results were confirmed in laboratory experiments using skin cells and skin-equivalent tissues and published in Proceedings of the National Academy of Sciences.