Preclinical research shows that higher doses of vitamin d slowed the progression of frailty among older mice
Most adults are either deficient in vitamin D (which is accompanied by clear symptoms) or have insufficient levels of the vitamin, which can go undetected. It is difficult to know how this insufficiency affects physical health or the vulnerability of older people to frailty.
A University at Buffalo study on 24-28-month old mice (equivalent to 65-80 year-old adults) has shown that frailty is slowed by what could be called \”over\”-supplementation of vitamin D. This condition is called \”hypersufficiency.\”
The research, published in Nutrients on September 30, builds upon previous research that Kenneth L. Seldeen Ph.D., first author and assistant research professor in the Department of Medicine at the Jacobs School of Medicine and Biomedical Sciences, UB has been doing for more than a ten-year period with Bruce R. Troen MD, professor of Medicine and chief of Geriatrics and Palliative Medicine and the director of the Center for Successful Aging in the Jacobs School.