Scientists extend mouse lifespan by 12%
Scientists have successfully extended the lifespan of mice using embryonic stem cell lines with extra-long Telomeres. Researchers were able to increase lifespan without genetic modifications. They also shed light on aging and techniques that could someday slow down the process.
The study, published on October 17 by Nature Communications, focuses on telomeres. Telomeres are DNA stretches found at the ends of chromosomes.
Telomeres are likened by some to the plastic tips at the ends of shoelaces because they protect the genetic material within chromosomes. Telomeres are also compared to \”molecular timers\” or bomb fuses because they shrink each time the cell divides. Eventually, this shrinkage causes the cell to die or stop dividing. The shortening of telomeres has been linked to aging, cancer and death.