The \”reboot\” of epigenetic genes reverses the aging process in mice, and may extend lifespan
Scientists from Harvard Medical School investigated the reasons why we age and found a way to reverse this process. The team found that epigenetic software glitches are responsible for the symptoms of ageing in mice. A system reboot could reverse these and extend lifespan.
The genome is the complete blueprint of DNA that can be found in each and every cell. It’s not all there is to it – an additional layer of information known as the epigenome sits on top of that and controls the genes turned on or off in various types of cells. The epigenome acts as a table-of-contents that guides different cells to the different chapters of the genome. Lung cells require very different instructions than heart cells.
Environment and lifestyle factors such as diet, exercise, and childhood experiences can change epigenetic expression throughout our lives. The rate of biological ageing has been associated with epigenetic changes, but it is unclear whether these changes are the cause of the symptoms or a symptom in themselves.