Rejuvenation of Old Cells reprogrammed as MSCs
In the past decade, mesenchymal stem cell (MSCs), due to the ability of these cells to promote tissue regeneration by simply being present and releasing signals has been a hot topic.
MSCs harvested from adults have been used in regenerative medicine for decades, with mixed results depending on their quality and age. In recent years, it was discovered that the effectiveness of these cells depends greatly on their age-related damage. This explains why MSC treatment sometimes works well for one person and not so well for another.
What about old cells that have been reprogrammed to pluripotency and then guided through cellular reprogramming into becoming mesenchymal cells?