New Discovery: Nicotinamide Riboside Supplementation Reduces Biomarkers of Alzheimer’s in the Brain

Researchers have linked supplementation with reduced biomarkers for Alzheimer’s disease in the brain

Researchers at the University of Delaware College of Health Sciences, in collaboration with a National Institute on Aging team, a division of National Institutes of Health (NIH), have determined for the first time that the naturally occurring dietary supplements known as nicotinamide riboside can enter the cerebral cortex.

Christopher Martens is an assistant professor of kinesiology, applied physiology, and director of Delaware Center for Cognitive Aging Research. Dr. Dimitrios Kapodgiannis is a senior researcher at the National Institute on Aging. This finding is important because it supports that NR can, once in the brain, alter metabolism of biological pathways implicated in neurodegenerative disorders like Alzheimer’s. They published their work in the journal Aging Cell.

Upon consumption of NR, it is easily converted into nicotinamide adenine dinucleotide(NAD+), a compound that is essential for cellular repair as well as the repair damaged DNA.


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