Neutral Evolution as a Key Factor for Lifespan and Ageing Variation of African Killifish

The lifespan and aging of a person is influenced by neutral evolution

The lifespan of different African killifish varies greatly, from a few weeks to several years. Scientists at the Max Planck Institute for Biology of Ageing, Cologne, investigated the evolution of different lifespans in nature. They discovered a mechanism that causes harmful mutations to accumulate in the fish’s genome and cause them to age quickly and live short lives. In humans, the mutations are primarily in genes that become active as we age.


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