High-Intensity Interval training: Boosting Telomere length and Telomerase activity in Non-Athletes

The effect of high-intensity interval training on telomere size and telomerase in young non-athletic men

Exercise is good for the mind, body and telomeres.

Introduction: The DNA portion of the chromosome that is located at the ends is called the telomere. Telomeres are important for cellular health. Exercise can help to control them. The present study aimed to examine the effects of 8 weeks high intensity interval training on telomere size and telomerase in young non-athletic men. In this semi-experimental research, 30 inactive students were randomly selected and divided into two groups: exercise (15 people), and control (15 persons). The exercise group did 8 weeks of HIIT exercises in 3 sessions per weekly with an intensity between 150 and 175% of maximum power (Pmax). The control group did not engage in regular sports activities. For the measurement of telomeres and telomerase activities, 10 ml blood was drawn from the subject’s brachial vein 24 hours prior to the first exercise session and the day after. To analyze differences within groups, the dependent t and independent t were used. Results: This study found that 8 weeks of HIIT in young non-athlete men led to a significant increase of telomere (P = 0.001) length and telomerase (P = 0.001). Conclusion: It appears that HIIT alters telomerase and telomere activity. These trainings may therefore have a positive impact on cell biology.


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