Exploring the Benefits of Regenerative Medicine in Skin Aging

Switching to Regenerative Medicine
Saranya Wyles MD, PhD, assistant Professor of Dermatology, Pharmacology and Regenerative Medicine in the Department of Dermatology at the Mayo Clinic, Rochester, Minnesota, presented the third presentation during the morning session, \”Emerging concepts.\” She discussed the signs of skin aging as well as the causes of aging. Wyles began by explaining how health care has evolved. There has been a change in the way medical professionals view medicine. In the past, doctors focused on fighting diseases like cancer, inflammatory disorders, and autoimmune disorders. The focus is shifting to the root cause, with a cure and how to rebuild your health. Regenerative medicine is the basis for determining how to improve the sequence in which patients receive different treatments and medications.

There is a molecular clock that the body follows for skin aging. Wyles’ laboratory focuses on cellular ageing. Within the clock, there are periods of genomic instabilities, telomere loss, and epigenetic changes.

We’ve heard much at this conference, about bio-stimulators, aesthetics and how to stimulate our internal mechanisms for regeneration. The opposite force to regeneration is the inhibitory ageing hallmarks, which includes cellular senescence. What is cell senescence, then? It is similar to apoptosis and proliferation. The cell enters a cell cycle stop, so that instead of dividing, apoptosis leads to cell death.


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