DNA Damage Response in Aging
DNA damage that results in genomic instability is one of the hallmarks of aging. We would like to draw attention today to a recent open-access review that examines the DNA damage reaction during aging.
The role of DNA damage
Researchers have suggested for years that DNA damage is the main reason we age, and also a factor in species longevity. Indeed, many species with long lifespans have genomes which are extremely stable, like bristlecone trees, who have a lifespan of more than 5000.