Cellular Senescence: A Sign of Aging
This article is part of a series of articles on the Hallmarks of Aging. The paper, published in 2013, divides the aging process into distinct categories (or \”hallmarks\”) to explain the way it works and the age-related diseases that result. Today we will look at a hallmark of cellular ageing.
What are senescent or aging cells?
As you get older, more and more of your cells will enter a senescent state. Senescent cells don’t divide or support tissues in which they reside; they instead emit potentially harmful chemical signals, encouraging nearby healthy cells into the same senescent condition. They can cause many problems, including a reduction in tissue repair and chronic inflammation.