Explore Dr. David Sinclair’s Research and Innovations to Reverse the Hallmarks Of Aging

Dr David Sinclair Interview Clips
It starts with a \”no\” but ends up being a \”yes\”. Only a few moments long.

A growing number of studies indicate the existence of a “metabolic clock” that controls aging. This clock is characterized by metabolic changes and a decline of metabolic homeostasis. Nine cellular markers of aging are present: stem cell exhaustion and exhaustion of stem cells, loss of proostasis (proteostasis), deregulated nutrient-sensing, epigenetic changes, and altered communication between cells. Each of these processes has been linked to metabolic alterations.


David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins–protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction–as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Dr David Sinclair suggested that aging was a disease, and that we might soon have the tools necessary to put it in remission. He also called for more international attention on the benefits to society and the economy of a world where billions of people could live longer and healthier lives.

Dr David Sinclair, co-founder and board member of many biotechnology companies, including Life Biosciences (Life Biosciences), Sirtris (Gencea), MetroBiotech (MetroBiotech), ArcBio (Liberty Biosecurity), and Cohbar.
He is co-founder, and also the co-chief editor, of the journal Aging. He has been awarded more than 35 honors and awards. He was listed in Time Magazine’s \”100 Most Influencial People in the World\” in 2014 and in Time’s top 50 healthcare professionals in 2018.

Disclaimer: This video does not constitute health advice and should not be used as a substitute for professional guidance. Video content is solely for informational purposes.

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