David Sinclair PhD, Exploring Aging Reversal – Unlocking the secrets of the epigenome

The Empowering Neurologist – David Perlmutter M.D. and Dr. David Sinclair
We all accept that aging is inevitable. There is no biological law that dictates we age. We’ve heard a lot of theories over the years to explain how we age, including damage to DNA, harmful chemicals called \”free-radicals\”, changes in our mitochondrial function, and many more.

Dr. David Sinclair is our guest today and he believes that the aging process is linked to information breakdown. He explains how our epigenome changes over time and has a powerful effect on our DNA. It is possible to reduce these epigenome changes. In fact, his research has revealed that epigenomes can be reprogrammed to a more youthful state.

David A. Sinclair is Professor of genetics at Harvard Medical School and the author of \”Lifespan: Why we age and why we don’t have to.\” He is the founding director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. TIME magazine named him one of \”100 most influential individuals in the world\” in 2014 and the top 50 most significant people in healthcare in 2018. He is also a founding editor of the journal Aging and a member of the American Federation for Aging Research. His research on NAD, resveratrol and reprogramming for reverse aging has been widely hailed and we will discuss these topics in our meeting.

Dr. Sinclair was awarded the Order of Australia’s equivalent of a Knighthood in 2018 for his work on human longevity and national security. Dr. Sinclair’s work has been featured in 60 Minutes and Today, The Wall Street Journal and The New York Times.

In closing, I really need to say that Lifespan (https://amzn.to/3sSoCNS) ranks as one of the most influential books I have ever read. Enjoy today’s conversation.

To stay current on Dr. Sinclair, follow him on Twitter (https://twitter.com/davidasinclair) and Instagram (https://www.instagram.com/davidsinclairphd/)


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